Anesthesia Management on Acquired Prothrombine Complex Deficiency

Abstract

Acquired prothrombin complex deficiency (APCD), often resulting from vitamin K deficiency, is a rare but potentially life-threatening hemorrhagic disorder in neonates and infants. This case report details the anesthesia management of a 36-day-old infant presenting with subdural hematoma and severe coagulopathy due to APCD. The patient underwent successful surgical intervention following correction of coagulopathy with vitamin K, fresh frozen plasma, and packed red cell transfusions. The report emphasizes the importance of comprehensive preoperative assessment, individualized coagulation therapy, intraoperative hemodynamic stability, and multidisciplinary collaboration to optimize outcomes in APCD cases. Advanced diagnostic tools and personalized treatment strategies are crucial for reducing perioperative complications and improving patient prognosis.